Meaning & use

Acantholysis

noun·Academic

Last updated

A medical condition in which the connections between skin cells break down, causing the cells to separate and the skin to blister.

See it in a sentence

A skin biopsy confirmed acantholysis, consistent with a diagnosis of pemphigus.

Acantholysis is a hallmark finding examined under the microscope in certain blistering skin diseases.

A note on using this word

From Greek akantha ("thorn," referring to the spiny look of separated cells) and lysis ("loosening"); a key diagnostic feature in dermatopathology.

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