Meaning & use
allosteric
Last updated
Relating to the regulation of a protein's activity by a molecule binding at a site other than the protein's active site.
See it in a sentence
The drug works as an allosteric inhibitor, changing the enzyme's shape rather than blocking its active site directly.
Researchers discovered an allosteric site on the receptor that could be targeted with a new class of medicines.
A note on using this word
A key term in biochemistry and pharmacology; allosteric regulation contrasts with 'competitive' regulation, which occurs directly at the active site.
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