Meaning & use

apoenzyme

noun·Advanced

Last updated

The protein part of an enzyme that becomes catalytically active only when combined with its nonprotein cofactor.

See it in a sentence

Without its cofactor, the apoenzyme alone cannot catalyze the reaction.

Researchers isolated the apoenzyme to study how it binds to different cofactors.

A note on using this word

A biochemistry term; an apoenzyme combined with its cofactor forms a complete, active 'holoenzyme.'

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