Meaning & use

base pair

noun·Advanced

Two complementary nucleotide bases, such as adenine and thymine, joined together in a DNA or RNA molecule.

See it in a sentence

A single mutation changed one base pair in the gene, altering the protein it produced.

Scientists counted billions of base pairs while mapping the entire human genome.

A note on using this word

In DNA, base pairs always follow strict pairing rules: adenine with thymine, and cytosine with guanine.

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