Meaning & use

cytotoxic

adjective, noun·Advancedmedicalbiologytechnical

Last updated

UK/ˌsaɪtəʊˈtɒksɪk/
US/ˌsaɪtoʊˈtɑːksɪk/

Meanings

  1. adjectivenot comparablemedical

    Poisonous to living cells, able to damage them or kill them.

    Grammar: Usually placed before a noun (cytotoxic drugs) or after be (the compound is cytotoxic).

    Patterns

    • cytotoxic to something
    • a cytotoxic drug
    • cytotoxic effect

    The compound proved cytotoxic to several kinds of tumor cells in the laboratory.

    Nurses wear gloves and gowns when preparing cytotoxic medicines.

    Some immune cells have a cytotoxic role, destroying cells infected by viruses.

  2. nounusually pluralmedical

    A drug that kills or stops the growth of cells, especially in chemotherapy.

    Grammar: Mostly used in the plural: the cytotoxics.

    Patterns

    • treated with cytotoxics

    Patients receiving cytotoxics often lose their hair temporarily.

    Hospitals store cytotoxics in clearly marked containers.

Word forms

pluralcytotoxics

Common combinations

cytotoxic drug
The oncologist explained how each cytotoxic drug would be given.
cytotoxic effect
Researchers measured the cytotoxic effect of the extract on cancer cells.
cytotoxic to cells
High doses of the chemical were cytotoxic to healthy cells too.
cytotoxic T cell
A cytotoxic T cell can recognize and kill an infected cell.
cytotoxic chemotherapy
Cytotoxic chemotherapy is often combined with surgery.

Synonyms and how they differ

toxic
Toxic is a general word for poisonous to anything, while cytotoxic specifically means poisonous to cells.
cytocidal
Cytocidal is a rarer, more purely technical word for killing cells; cytotoxic can also mean harmful without necessarily killing.
cell-killing
Cell-killing is a plain-English description, less formal than cytotoxic and rarely used in medical writing.

Opposites

cytoprotective

Word family

cytotoxicity noun
the quality of being toxic to cells
cytotoxin noun
a substance that is poisonous to cells
cytology noun
the study of cells
toxic adjective
poisonous

Commonly confused: cytotoxic or cytostatic?

cytotoxic vs cytostatic

Cytostatic means stopping cells from multiplying without killing them, whereas cytotoxic means damaging or killing them.

Practice

Doctors describe a drug as cytotoxic when it is ___.

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