Meaning & use

homologous chromosome

noun·Academicbiologytechnical

Last updated

UK/həˈmɒləɡəs ˈkrəʊməsəʊm/
US/həˈmɑːləɡəs ˈkroʊməsoʊm/

Meaning

  1. nouncountablebiology

    Either member of a matched pair of chromosomes that carry the same genes in the same order, with one copy coming from each parent.

    Grammar: Usually plural or paired: a cell holds two homologous chromosomes of each type.

    Patterns

    • a pair of homologous chromosomes
    • homologous chromosomes separate
    • crossing over between homologous chromosomes

    Chromosome 7 from your mother and chromosome 7 from your father are homologous chromosomes.

    During meiosis, each homologous chromosome lines up beside its partner before the two are pulled apart.

    The two homologous chromosomes may carry different versions of the same gene.

Word forms

pluralhomologous chromosomes

Common combinations

pair of homologous chromosomes
Humans have 23 pairs of homologous chromosomes in most body cells.
homologous chromosomes pair up
Early in meiosis, homologous chromosomes pair up along their whole length.
separation of homologous chromosomes
The separation of homologous chromosomes gives each egg or sperm cell half the usual set.
crossing over between homologous chromosomes
Crossing over between homologous chromosomes shuffles the genes passed to offspring.
maternal and paternal homologous chromosomes
Each cell contains maternal and paternal homologous chromosomes that match gene for gene.

Synonyms and how they differ

homolog
Homolog is a shorter, mostly spoken or lab-setting form, and it can also refer to similar genes or structures, not only whole chromosomes.
homologue
Homologue is the British spelling of homolog and carries the same broad scientific meaning.
chromosome pair
Chromosome pair is a looser everyday phrase that does not stress that the two partners match in gene content.

Opposites

sex chromosomes (in males)

Word family

homology noun
similarity of structure or origin between parts of different organisms or molecules
homologous adjective
having matching structure or origin
chromosome noun
a threadlike structure in a cell that carries genes
chromosomal adjective
relating to chromosomes

Commonly confused: homologous chromosome or sister chromatid?

homologous chromosome vs sister chromatid

Sister chromatids are two identical copies of one chromosome joined together, whereas homologous chromosomes are two separate chromosomes, one from each parent, that are similar but not identical.

Practice

Which statement correctly describes a pair of homologous chromosomes?

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