Meaning & use

monovalent

adjective·Advancedtechnicalchemistrymedical

Last updated

UK/ˌmɒnəʊˈveɪlənt/
US/ˌmɑːnoʊˈveɪlənt/

Meanings

  1. adjectivenot comparablechemistry

    Describing an atom, ion, or group that has a valence of one, so it can bond with just one hydrogen atom.

    Grammar: Used before a noun or after be: a monovalent ion.

    Patterns

    • a monovalent ion

    Sodium forms a monovalent cation with a charge of plus one.

    Chlorine is monovalent in a compound such as sodium chloride.

    The textbook lists monovalent elements in the first column.

  2. adjectivenot comparablemedical

    Describing a vaccine or antibody that works against one single strain or antigen.

    Grammar: Used before a noun: a monovalent vaccine.

    Patterns

    • a monovalent vaccine

    The clinic used a monovalent vaccine aimed at one virus strain.

    Researchers compared a monovalent antibody with a multivalent one.

    A monovalent shot protects against only a single type.

Common combinations

monovalent ion
A potassium ion is a monovalent ion.
monovalent vaccine
The monovalent vaccine targets one strain.
monovalent cation
Sodium is a monovalent cation in solution.
monovalent antibody
A monovalent antibody binds a single site.

Synonyms and how they differ

univalent
Univalent means the same as monovalent in chemistry but is the older, less used term.
single-strain
Single-strain is a plain phrase in vaccines, while monovalent is the formal technical word.
monofunctional
Monofunctional describes a molecule with one reactive site, which is related but not limited to valence.

Opposites

polyvalentmultivalent

Word family

valence noun
the combining power of an atom
divalent adjective
having a valence of two
polyvalent adjective
having several valences or targeting several strains
monovalence noun
the state of being monovalent

Commonly confused: monovalent or monolithic? monovalent or bivalent?

monovalent vs monolithic

Monolithic means large and uniform like a single stone, with no link to valence.

monovalent vs bivalent

Bivalent means having a valence of two, so it is the next step up, not the same.

Practice

A sodium ion carries a single positive charge and is described as ___.

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