Meaning & use
Nondisjunction
Last updated
The failure of paired chromosomes to separate properly during cell division, resulting in cells with an abnormal number of chromosomes.
See it in a sentence
Nondisjunction during egg formation is the most common cause of Down syndrome.
Researchers study nondisjunction in fruit flies to understand how chromosome errors arise.
A note on using this word
Nondisjunction can occur during either meiosis or mitosis and is a major source of genetic disorders caused by an incorrect chromosome count.
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