Meaning & use

periplasm

noun·Advanced

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In biology, the space between the inner and outer membranes of certain bacterial cells.

See it in a sentence

Enzymes secreted into the periplasm help the bacterium break down large molecules before they enter the cell.

Researchers study the periplasm to understand how gram-negative bacteria resist antibiotics.

A note on using this word

A specialized term used mainly in microbiology; it applies chiefly to gram-negative bacteria, which have both inner and outer membranes.

Words with a similar meaning

periplasmic space

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