Meaning & use

proteolytic

adjective·Advancedtechnical

Last updated

UK/ˌprəʊtiəˈlɪtɪk/
US/ˌproʊtiəˈlɪtɪk/

Meaning

  1. adjectivenot comparabletechnical

    Relating to the breaking down of proteins into smaller peptides or amino acids.

    Grammar: Used before a noun, especially 'enzyme' or 'activity'; it has no comparative form.

    Patterns

    • proteolytic enzyme
    • proteolytic activity
    • proteolytic cleavage

    Pepsin is a proteolytic enzyme that works in the stomach.

    The researchers measured proteolytic activity in the blood samples.

    Proteolytic cleavage turns the inactive protein into its active form.

Common combinations

proteolytic enzyme
Trypsin is a proteolytic enzyme used in the lab to detach cells.
proteolytic activity
Heat destroys most of the proteolytic activity in the extract.
proteolytic cleavage
Proteolytic cleavage releases the hormone from its precursor.
proteolytic degradation
The drug is protected from proteolytic degradation in the gut.

Synonyms and how they differ

peptidase
This is a noun for an enzyme that cuts proteins, not an adjective; use it when you name the enzyme itself.
proteinase
Another noun for a protein-splitting enzyme; 'proteolytic' describes the enzyme's action, not the enzyme.

Word family

proteolysis noun
The process of breaking down proteins.
protease noun
An enzyme that carries out proteolysis.

Commonly confused: proteolytic or protean?

proteolytic vs protean

'Protean' means easily changing shape or form, while 'proteolytic' is strictly about breaking down proteins.

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