Meaning & use

Protonate

verb·Academic

Last updated

To add a proton to an atom, molecule, or ion, typically forming a positively charged species.

See it in a sentence

The enzyme works by protonating a specific amino acid in the active site.

In acidic solution, the amine group readily protonates.

A note on using this word

A core concept in acid-base chemistry: acids are often defined as substances that protonate other molecules.

Words with a similar meaning

ionize

Choose a synonym to suit the sentence. Meanings can overlap without being identical.

Words with an opposite meaning

deprotonate

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