Meaning & use

Substituent

noun·Academic

Last updated

An atom or group of atoms that replaces one or more hydrogen atoms in a parent chemical compound.

See it in a sentence

Adding a chlorine substituent to the benzene ring changed the compound's reactivity.

Chemists classify substituents as either electron-donating or electron-withdrawing based on their effect on the ring.

A note on using this word

Substituents are central to organic chemistry naming rules, since a compound's full name typically lists each substituent along with its position on the parent chain.

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