Meaning & use

Upregulated

adjective·Academic

Last updated

Increased in level of expression or activity, especially referring to a gene, protein, or biological process.

See it in a sentence

Researchers found that the stress-response gene was upregulated in cells exposed to high temperatures.

Insulin receptors can become upregulated when blood sugar levels are chronically low.

A note on using this word

"Upregulated" is standard terminology in molecular biology, describing a cell's increase in the quantity of a cellular component such as RNA or protein.

Words with a similar meaning

increasedamplified

Choose a synonym to suit the sentence. Meanings can overlap without being identical.

Words with an opposite meaning

downregulated

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