Meaning & use

antigen

noun·Academicmedicalbiology

Last updated

UK/ˈæn.tɪ.dʒən/
US/ˈæn.tɪ.dʒən/

Meanings

  1. nouncountable

    A substance, such as part of a virus or bacterium, that causes the immune system to produce a response against it.

    Grammar: Takes a plural: antigens. A core biology and medicine term.

    Patterns

    • an antigen triggers something
    • an antigen test

    The spike protein acts as an antigen that the immune system learns to recognize.

    Exposure to the antigen caused the body to produce antibodies.

  2. nouncountable

    A substance detected in a test designed to show whether a person currently has a particular infection.

    Grammar: Used in compounds like antigen test.

    Patterns

    • a rapid antigen test
    • test positive for an antigen

    His rapid antigen test came back positive, so he stayed home from work.

    Antigen tests are cheaper and faster than PCR tests, though slightly less sensitive.

Word forms

pluralantigens

Common combinations

viral antigen
The vaccine presents a harmless viral antigen to train the immune system.
antigen test
Passengers were asked to show a negative antigen test before boarding.
tumor antigen
Researchers are developing drugs that target specific tumor antigens.
antigen presentation
Dendritic cells specialize in antigen presentation to T cells.

Synonyms and how they differ

immunogen
A narrower technical term: an antigen that actually provokes an immune response; some antigens are recognized without provoking one.

Opposites

Word family

antigenic adjective
Able to act as or relating to an antigen.
antigenicity noun
The capacity of a substance to act as an antigen.

Commonly confused: antigen or antibody?

antigen vs antibody

The antigen is the foreign invader that triggers the response; the antibody is the protein the immune system makes to attack it.

Practice

In an immune response, the ___ is the trigger and the ___ is what the body makes to fight it.

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